NAD+
Cellular energy. Metabolic efficiency. Whole‑body resilience.
**To ensure safe, personalized care, a provider consultation is required once per calendar year. A $30 fee applies.**
WHAT IS NAD+
NAD+ (Nicotinamide Adenine Dinucleotide) is an essential pyridine nucleotide found in every living cell. It functions as a redox coenzyme, cycling between its oxidized (NAD+) and reduced (NADH) forms to drive mitochondrial ATP production through glycolysis, the TCA cycle, and oxidative phosphorylation.
Beyond energy metabolism, NAD+ is a required substrate for several enzyme families — including sirtuins, PARPs, and CD38/CD157. These systems govern DNA repair, chromatin remodeling, calcium signaling, mitochondrial biogenesis, and cellular stress responses. Together, these pathways maintain genomic stability, support mitochondrial functioning, and modulate the molecular processes associated with aging and cellular resilience.
WHAT DOES IT SUPPORT?
- Cellular Energy Production — Supports efficient mitochondrial ATP generation.
- DNA Repair & Genomic Stability — Fuels enzymes involved in maintaining cellular integrity.
- Longevity Pathways — Activates sirtuins associated with cellular protection and healthy aging.
- Metabolic Regulation — Helps maintain balanced metabolic signaling and cellular efficiency.
- Cognitive Clarity — Supports pathways involved in focus, mental stamina, and resilience.
- Cellular Stress Response — Assists systems that help cells adapt and recover.
HOW IT IMPACTS YOUR WELLNESS
When NAD+ is available in healthy amounts, your cells operate with greater efficiency — producing steadier energy, repairing everyday cellular stress, and supporting balanced metabolic signaling. These behind‑the‑scenes processes can translate into clearer thinking, more consistent vitality, smoother recovery, and an overall sense of feeling refreshed and well‑supported.
THE NATURAL DECLINE
NAD+ levels naturally decrease with age due to increased cellular stress, DNA repair demands, and changes in metabolic signaling. As these pathways work harder over time, the body uses more NAD+ than it can efficiently replenish, leading to lower overall availability.




